| ORKNEYISLANDS | What is separated from the mainland by the Pentland Firth? (6,7) |
| ORKNEY | A group of over 70 islands off the N coast of Scotland separated from the mainland by the Pentland Firth |
| EDINBURGH | City to the northeast of the Pentland Hills (9) |
| ANGLESEY | Which Welsh island is separated from the mainland by the Menai Strait? (8) |
| FUEGO | Archipelago at the southern extremity of South America separated from the mainland by the Strait of Magellan; Spanish, ' land of fire' (6,3,5) |
| NEWFOUNDLAND | Large island of E Canada separated from the mainland by the Strait of Belle Isle (12) |
| THANET | Isle of ?, area of Kent formerly separated from the mainland by the Wantsum Channel |
| SKYE | Scottish island separated from the mainland by the Kyle of Lochalsh (4) |
| ISLEOF | Area of NE Kent formerly separated from the mainland by the Wantsum Channel (4,2,6) |
| MERRYMENOFMEY | Tidal race in Pentland Firth (5,3,2,3) |
| HANOI | In which Asian city is Hoan Kiem Lake, also known as Lake of the Restored Sword, where the Temple of the Jade Mountain is connected to the mainland by the red The Huc Bridge? (5) |
| JURA | Island in the Inner Hebrides that is separated from the Scottish mainland by the Sound of ... (4) |
| ISLE | Australian state separated from the mainland by Bass Strait, Tasmania is also called the Apple ... |
| SHIKOKU | The smallest of the four main islands of Japan. It is separated from Honshu by the Inland Sea (north) and the Kii Strait (east) and from Kyushu by the Bungo Strait (west). (7) |
| CANVEYISLAND | Area of land in the Thames Estuary in Essex, separated from the mainland by a network of creeks (6,6) |
| EUBOEA | Greek island believed to have been separated from the mainland by an earthquake |
| OLAND | Second-largest island of Sweden, separated from the mainland by Kalmar Sound (5) |
| ORPHAN | In typography, the first line of a paragraph which is separated from the rest of the paragraph by a column break (6) |
| KEYS | Florida ___ (area connected to the mainland by the Overseas Highway) |
| WHEY | The watery part of milk, which is separated from the curd in cheesemaking (4) |