| EMI | One of the Big Four record labels, until it became the Big Three |
| SECONDNATURE | Scanned route until it became instinctive? |
| DJM | Elton John's label until 1976 (1,1,1) |
| LNER | Abbreviated form of the second-largest of the "Big Four" railway companies created by the Railways Act of 1921 |
| DWAYNE | ___ Wade one of the Big Three of basketball who retired in 2019 |
| GEORGE | Regnal name of British Monarch on the throne at the time of the Big Four Grouping in 1923 (6) |
| UMG | One of the Big Three labels |
| ROUX | Surname of French brothers Albert and Michel, owners of Le Gavroche when it became the first UK restaurant to gain three Michelin stars (4) |
| SHERATON | The last to die of the 'big three' 18th-century English furniture-makers (8) |
| FITCH | One of the big three credit rating agencies (5) |
| YALTA | Where is Livadia Palace, the site of a 1945 meeting between the Big Three powers? (5) |
| SONY | One of the "Big Four" labels |
| KPMG | One of the "Big Four" accountancy firms. (1,1,1,1) |
| EY | One of the big four accounting firms, abbr. (2) |
| PWC | One of the Big Four accounting firms. (1,1,1) |
| ERNST | EY (___ & Young) is one of the Big Four accounting firms. (5) |
| CBS | One of the big three US TV networks |
| AXILLARY | It was to do with the jawbone but when meal starter was gone it became the armpit (8) |
| GRAIL | According to legend, what holy object was used by Christ at the Last Supper and finding it became the quest of medieval romances? (5) |
| NAIROBI | Capital of Kenya, founded in 1899; it became the capital in 1905 (7) |
