| GREASYPOLE | A son blocking dull European's difficult route to the top |
| NEGOTIATE | One can manage a difficult route successfully, but had to work at it (9) |
| WEIGHUP | Assess the route to the top, allegedly (5,2) |
| HALFWAYUP | At a central point en route to the top |
| CLIMB | Conservative member's route to the top? |
| SKILIFT | Comedy sketch about student providing route to the top? (3,4) |
| VANITY | From "empty", word for conceit, excessive pride or self-love; a Bunyanesque town through which pilgrims pass en route to the Celestial City; or, in the US, a dressing-table (6) |
| PATHWAY | Why a tap like this produces a route to the brain (7) |
| TRAIL | The Oregon ___, a major 19th-century emigrant route to the American West (5) |
| THUNDERROAD | Bruce Springsteen song about a route to the Oklahoma City arena? |
| NAVIGATE | Find a route to the labourer's entrance, we hear (8) |
| CHAMPSELYSEES | Top horse with second place in Cambridgeshire eyes route to The Arc |
| REDSEA | Tangled reeds near a trade route to the East (3,3) |
| LOSESTHEHATCHES | Misplaces the route to the airlock, maybe? |
| COASTROAD | The nearest route to the sea |
| AVIATORS | Fliers on a classic route to the hills (8) |
| ACUTELY | How one may be aware of a short route to the city (7) |
| ENABLE | Allow bishop to enter route to the north east |
| THROAT | The route to the interior (6) |
| MAINLINES | Principal routes to the ocean lie around the north and the south (4,5) |