Across and Down

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There are 14 clues with the answer 'MAINLINES'
# CLUE
1.
Principal routes to the ocean lie around the north and the south (4,5)
2.
Injects horse maybe with a little magnesium mixed in saline (9)
3.
Zero returns in US state's trunk routes (4,5)
4.
Zero returns in U.S. state's trunk routes (4,5)
5.
Principal Via routes
6.
Injects drug in Isle of Man recklessly without odd feeling at first (9)
7.
Railroads' primary routes
8.
Principal routes (2 wds)
9.
Chief ways to be at home in Belgian city (4,5)
10.
Principal railroad routes
11.
Puts
12.
Injects
13.
Principal ways mothers used to keep under control (4,5)
14.
Do palmists focus on these busiest routes? (4,5)