| HUNTINGTON | ___'s disease: genetic disorder which affects muscle coordination and leads to cognitive disorder (10) |
| DEMENTIA | Wrongly detain me for cognitive disorder (8) |
| TRICEPS | Rep's tic affects muscles (7) |
| ANABOLICSTEROID | Calibration does affect muscle-building drug (8,7) |
| ATAXY | Loss of muscle coordination |
| ATAXIC | Showing lack of muscle coordination |
| ATAXIA | Loss of muscle coordination |
| WHONEEDSIT | "You must give that to the U.N.'s disease-tracking agency"? |
| APHA | U.S. disease-prevention org. |
| MENIERE | ---'s disease, inner-ear condition (7) |
| HOLBYCITY | Medical drama of blotchy disorder one contracted at start of year (5,4) |
| GLEANER | General disorder one gathers |
| ADHD | Genetic disorder that may cause hyperactivity and inattentiveness (1,1,1,1) |
| PERUSAL | Paddington's point of departure, and leads to Slough, Acton, Langley and Reading (7) |
| DUDGEON | Failure is upsetting, for example, for old and new and leads to deep resentment (7) |
| CAMERA | Snapper starts to come apart, making excuses and leads to regretful apologies (6) |
| BSE | Disease of cattle which affects the central nervous system (1,1,1) |
| DISTRIBUTION | Most of the issue is charged and leads to handouts (12) |
| LANGUOR | Most of the terrain is uphill, endlessly rough and leads to fatigue (7) |
| AUTISM | Disorder which causes limited responses to others and withdrawal from reality (6) |
