| GILA | ___ monster, a large, venomous, brightly coloured lizard native to Mexico and the Southwestern US (4) |
| GILAMONSTER | Large, venomous, brightly coloured lizard inhabiting deserts of the southwestern US and Mexico (4,7) |
| IGUANA | Type of lizard native to Mexico (6) |
| MESA | Flat-topped hill with steep sides, common in the southwestern US (4) |
| GUAYULE | Bushy shrub in the aster family of Mexico and the southwestern US; a source of latex (7) |
| MESCAL | Alternative name for the peyote cactus (Lophophora williamsii) of Mexico and the southwestern US (6) |
| PEYOTE | Spineless globe-shaped cactus of Mexico and the southwestern US that is also called mescal (6) |
| BAHIAGRASS | Common name for Paspalum notatum, which is native to Mexico and South America |
| POINSETTIA | Shrub native to Mexico and Central America, widely cultivated for its showy scarlet bracts (10) |
| SOMBRERO | A broad-brimmed hat, typically worn in Mexico and the southwestern U.S. (8) |
| DAHLIA | Showy perennial flower native to Mexico and Central America (6) |
| MONITOR | A large lizard native to Africa, Asia and Oceania (7) |
| SULUSEA | Region of the western North Pacific between northeastern Borneo and the southwestern islands of the Philippines (4,3) |
| KOMODODRAGON | A large monitorr lizard native to Indonesia (6,6) |
| KOMODO | Largest living species of lizard, native to the Lesser Sunda Islands of Indonesia (6,6) |
| DRAGON | Largest living species of lizard, native to the Lesser Sunda Islands of Indonesia (6,6) |
| SISALHEMP | Fibre made from the leaves of a plant native to Mexico (5,4) |
| EYE | One-of-a-kind monster: A cyclops is a mythical creature with one___ in the center of his forehead |
| CETE | A sea monster; a whale; or, from "assembly", a company of badgers (4) |
| COBRA | A large venomous snake which when irritated dilates its neck like a hood |
