| GILA | ___ monster (reptile of the American Southwest) |
| ALLIGATOR | Large, snapping reptile of the American South. |
| SAGEBRUSHLIZARD | Reptile of the American West |
| JOSHUATREE | Tall, branching yucca of the American Southwest (2 wds.) |
| NAVAHOS | Natives of the American Southwest |
| MESA | Flat-topped hill of the American southwest |
| ROADRUNNER | Bird of the American Southwest (10) |
| APACHE | Indigenous people of the American Southwest |
| KITCARSON | Renowned 19th century trapper, guide, military scout, Indian agent, soldier and rancher of the American Southwest |
| RINGTAIL | Name given to several creatures, including Bassariscus astutus, which inhabits arid northern Mexico and the American Southwest |
| PTEROSAUR | Reptile of the Jurassic and Cretaceous periods such as the quetzalcoatlus, the largest flying animal |
| PTERO | Word prefixed to "saur" to form the name of a flying reptile of the Triassic and Cretaceous periods |
| RATTLESNAKE | Venomous reptile of the Americas, the tail of which can produce a threatening sound (11) |
| TUATARA | Greenish-grey reptile of the family Sphenodontidae that occurs only on certain small islands of New |
| CORALSNAKE | Venomous reptile of the cobra family remembered in the rhyme: "red to yellow, kill a fellow; red to black, venom lack" (5,5) |
| DINOSAUR | Any extinct terrestrial reptile of the orders Saurischia and Ornithischia, dating from the Mesozoic era (8) |
| PLESIOSAUR | What large reptile of the Mesozoic era with a broad flat body and large paddle-like limbs lived in the sea? (10) |
| CHELONIAN | Any reptile of the order Testudines, comprising the tortoises, turtles and terrapins (9) |
| GARTERSNAKE | North American reptile of the genus Thamnophis typically marked with longitudinal stripes (6,5) |
| PTERODACTYL | Common name for a flying reptile of the late Jurassic; from the Greek for 'wing finger' (11) |
