| LETTICE | ___ Knollys, the noblewoman who secretly wed Robert Dudley, Elizabeth I's favourite, in 1578 (7) |
| RALEIGH | English writer, soldier, courtier and explorer who first sailed to the New World in 1578 (6,7) |
| WALTER | English writer, soldier, courtier and explorer who first sailed to the New World in 1578 (6,7) |
| FOLKESTONE | English port town in which physician William Harvey, discoverer of total circulation, was born in 1578 |
| ROBSART | Amy -, first wife of Robert Dudley, Earl of Leicester featured in 1821 Walter Scott novel Kenilworth (7) |
| KNOLLYS | Lettice ___, whose secret marriage to Robert Dudley was regarded as an unforgivable betrayal by Elizabeth I (7) |
| EUPHUES | 1578 novel by John Lyly subtitled The Anatomy of Wit (7) |
| PETUNIA | Plant is favourite - any number I planted in middle of quad |
| SPANIEL | Dog which was a royal favourite in the 17th Century and appears in many paintings (7) |
| NOSTRUM | No way liquor is favourite remedy (7) |
| ALMONDS | Edible oval nuts, a favourite in the Christmas nut bowl (7) |
| WHIPPET | Would it beat the favourite in a race? (7) |
| COMPETE | Vie with the favourite in? Come! (7) |
| ABELARD | A French theologian who secretly married his pupil Heloise |
| TEPIDLY | Half-heartedly backing favourite in a sluggish way (7) |
| RANIPET | Queen favourite in industrial town (7) |
| CRICKET | Summer favourite in box H (7) |
| PALAVER | Old man and one-time court favourite in fuss (7) |
| INFANCY | Popular favourite in childhood |
| POPULAR | Favourite; in vogue? |