| VEINED | With blood vessels in evidence, heart's a-flutter (6) |
| THREATENS | Menaces sent heart a-flutter (9) |
| REDEYE | Effect in photographs caused by reflection from blood vessels in the retina (3,3) |
| VENOSE | Marked with blood vessels |
| VENOMOUS | Toxic way of working in dealing with blood vessels (8) |
| ANGIO | Prefix having to do with blood vessels |
| DECONGESTANT | It reduces swelling of blood vessels in nose (12) |
| DIABETES | Condition that can cause damage to blood vessels in the kidneys, leading to potential kidney damage. (8) |
| STROKE | A beat of a heart; a hit of a ball in golf or tennis; a solidus or virgule; a pull of an oar; a sound of a clock's chime; or, a sudden sweep of genius or luck (6) |
| HIATUS | Hearts, a suit that's played in break (6) |
| ARTERY | Blood vessel in paintings found by the queen and youth leader (6) |
| SLEEVE | An arm of a garment, where one may figuratively wear their heart; a cover for an LP or a CD; or, a windsock (6) |
| CORNEA | Name inscribed in heart -- a bit of a looker (6) |
| LACOCK | With William Henry Fox Talbot's former abbey and home at its heart, a National Trust village in Wiltshire, where scenes from Cranford, Pride and Prejudice and Downton Abbey were filmed (6) |
| INSTAL | Isn't having change of heart -- a learner put in place (6) |
| LOVATO | Demi with the 2012 hit "Give Your Heart a Break" |
| TURKEY | Old guard losing heart a total failure (6) |
| LONELY | After 50, single lady losing heart a may feel this? (6) |
| TICKER | Informal word for the heart, a watch or anything that beats/clicks (6) |
| RECORD | From the Latin for "heart", a word originally meaning "call to mind, learn by heart", later any chronicle, log, memorandum or register (6) |
