| ROOM | With 4 Down. The ____ on the ____: Bond's first and most famous novel |
| HARROW | One of the country's oldest and most famous public schools, founded by John Lyon in 1571 (6) |
| ROMEN | Oldest and most famous theatre in Russia |
| KANEANDABEL | Jeffrey Archer's most famous novel? (4,3,4) |
| VIAAPPIA | One of the first and most important Roman roads, connecting the empire's capital with Brindisi (3,5) |
| LEWWALLACE | His most famous novel is subtitled "A Tale of the Christ" |
| MANCHA | Last word in the full title of Cervantes's most famous novel |
| FLAUBERT | Gustave ___, French author whose most famous novel is Madame Bovary |
| OMOO | Herman Melville's most-famous novel (crossword-wise) |
| HORSE | A ___ With No Name: 1971 single by America, their first and most successful (5) |
| PENICILLIN | One of the first and most widely used antibiotic agents |
| MOLLFLANDERS | 'The Fortunes and Misfortunes of the famous -', novel by Daniel Defoe (4,8) |
| ALDA | 32 years elapsed between his first and most recent Emmys |
| NOANGEL | Dido’s first and most successful album, released internationally in 2001 |
| MILL | The ___ on the Floss: 1860 novel by Mary Ann Evans, who used the pen name George Eliot (4) |
| SEA | The Old Man and The ___: Ernest Hemingway's famous novel? |
| MAN | The Old ___ and The Sea: Ernest Hemingway's famous novel? |
| ECSTASY | The Agony And The ___ : Irving Stone's famous novel ? (7) |
| EARLIEST | First and most like a noble, could one say? |
| SPECIAL | First and most important (7) |
