| COMEQUICKLY | With 35A, comment by 42A upon his discovery of 17A |
| EUREKA | Exclamation attributed to Archimedes upon his discovery of displacement (6) |
| ACT | With 35A, dramatize |
| TELESCOPE | Optical instrument used by Galileo Galilei for many of his scientific observations of 17a 35a 24d and 43d |
| BRADLEY | Scientist known for his discovery of the aberration of light and for observing the oscillation of Earth's axis (nutation), who succeeded Edmond Halley as Astronomer Royal in 1742 (7) |
| LEOESAKI | Japanese physicist who shared the 1973 Nobel Prize for Physics with Ivar Giaever and Brian David Josephson for his discovery of the phenomenon of electron tunnelling |
| LAUE | Max von -; physicist awarded a Nobel Prize for his discovery of the diffraction of X-rays by crystals (4) |
| EINSTEIN | Recipient of a Nobel prize "for his discovery of the law of the photoelectric effect" |
| SHECHTMAN | Recipient of the 2011 Nobel Prize for his discovery of quasicrystals, he also ran for president in his home country Israel (last name only) |
| DOPPLER | Austrian physicist, d. 1853 famous for his discovery of the effect of movement on perceived waveleng |
| ALVAREZ | Nobel Prize-winning physicist noted for his discovery of the iridium layer and his theory that the m |
| GALVANI | Which Italian anatomist (Luigi ___) is best known for his discovery of the twitching of frogs' legs in an $$ % |
| MENDEL | Monk whose experiments breeding pea plants led to his discovery of genes, earning him recognition as the father of genetics, albeit posthumously (6) |
| HERSCHEL | Composer whose construction of a telescope led to his discovery of Uranus in 1781 and subsequent appointment as court astronomer to George III the following year (8) |
| ARYABHATA | Ancient Indian mathematician known for his discovery of the value of pi, among other things |
| FRANKLIN | American polymath known for his discovery of the electrical properties of lightning, among other things (surname only) |
| OTTOHAHN | German chemist awarded the Nobel Prize in Chemistry in 1944 'for his discovery of the fission of heavy nuclei' (4,4) |
| IVAN | Forename of a physiologist whose experiments feeding dogs led to his discovery of classical conditioning (4) |
| CROOKES | William -; scientist noted for his discovery of thallium (7) |
| RONTGEN | German physicist known for his discovery of X-rays |
