| HARTNELL | William, actor who was the first Doctor Who (8) |
| JENNER | Edward - - -, English scientist who was the first doctor to introduce and study the smallpox vaccine (6) |
| FICHTNER | William -, actor who played Butch Cavendish in 2013 Western film The Lone Ranger (8) |
| OBSCURED | Sob uncontrollably as remedy given by first doctor is garbled (8) |
| WILLIAMHARTNELL | First Doctor Who actor (7,8) |
| DAVID | Scottish actor who was the Tenth Doctor in the TV series Doctor Who and is the sonin-law of Fifth Doctor Peter Davison (5,7) |
| TENNANT | Scottish actor who was the Tenth Doctor in the TV series Doctor Who and is the sonin-law of Fifth Doctor Peter Davison (5,7) |
| SHATNER | William, actor who played the title role in the television series TJ Hooker (7) |
| DUELL | William --, actor who played Jim Sefelt in the 1975 film 'One Flew Over the Cuckoo's Nest' (5) |
| DAVIDTENNANT | Scottish actor who was the Tenth Doctor in the TV series Doctor Who |
| EDWARDJENNER | English scientist, the first doctor to introduce and study the smallpox vaccine (6,6) |
| DRONE | The first doctor to be a non-worker? (5) |
| LISTER | The first doctor to use antiseptic treatment in surgery (6,6) |
| JOSEPH | The first doctor to use antiseptic treatment in surgery (6,6) |
| SCOTT | Seann William -, actor who played Bo Duke in 2005 action-comedy film The Dukes of Hazzard |
| ROACHE | William -, actor who has played Ken Barlow in ITV soap Coronation Street since 1960 (6) |
| GAUNT | William -, actor who starred as Arthur Crabtree in 1980s BBC TV sitcom No Place Like Home (5) |
| ASH | William -, actor who played Christopher Mead in BBC TV series Waterloo Road from 2009-11 (3) |
| HURT | Actor who was the voice of Aragorn in the original 1978 film version of The Lord of the Rings (4) |
| BOGARDE | Dirk ___, English actor who was the first British president of the jury at the Cannes Film Festival |
