| HARTNELL | William -, the first Doctor in Doctor Who (8) |
| MEDIC | Physician sending compiler to first doctor in charge (5) |
| TOMBAKER | Actor who played the fourth incarnation of The Doctor in Doctor Who, noted for his scarf and fedora (3,5) |
| OBSCURED | Sob uncontrollably as remedy given by first doctor is garbled (8) |
| JENNER | Edward - - -, English scientist who was the first doctor to introduce and study the smallpox vaccine (6) |
| LISTER | The first doctor to use antiseptic treatment in surgery (6,6) |
| JOSEPH | The first doctor to use antiseptic treatment in surgery (6,6) |
| SMITH | Actor whose roles include an incarnation of The Doctor in Doctor Who and Prince Philip in The Crown (5) |
| BAKER | Tom -; English actor who played the fourth incarnation of the Doctor in Doctor Who (5) |
| CAPALDI | Actor who portrayed the 12th incarnation of the Doctor in Doctor Who, Peter ... (7) |
| MATTSMITH | Morbius star who was the 11th incarnation of the Doctor in Doctor Who (4,5) |
| PETER | Actor who played the 12th incarnation of The Doctor in Doctor Who, _ Capaldi (5) |
| MCCOY | Sylvester _, actor who played the seventh incarnation of the Doctor in Doctor Who (5) |
| DAVID | Which actor, the 10th Doctor in Doctor Who, married Georgia, daughter of Peter Davison, the fifth Doctor? (5,7) |
| TENNANT | Which actor, the 10th Doctor in Doctor Who, married Georgia, daughter of Peter Davison, the fifth Doctor? (5,7) |
| ECCLESTON | Actor who played the Ninth Doctor in Doctor Who, Christopher ... (9) |
| HURT | John _, late actor who played the War Doctor in Doctor Who (4) |
| CHRISTOPHER | Actor who played the Ninth Doctor in Doctor Who (11,9) |
| MATT | _ Smith, actor who has played The Doctor in Doctor Who (4) |
| EDWARDJENNER | English scientist, the first doctor to introduce and study the smallpox vaccine (6,6) |