| CAFFEINE | Which bitter alkaloid is obtained from coffee (8) |
| QUININE | Which bitter alkaloid is used to treat malaria (7) |
| COCAINE | Which bitter alkaloid was formerly used as a local anaesthetic (7) |
| BERGAMOT | Oil is obtained from this Italian city by the ton (8) |
| ALLSPICE | What is obtained from the berry of the pimento tree (8) |
| CROCUSES | Saffron is obtained from these corms (8) |
| OILWELLS | Petroleum is obtained from these. (3,5) |
| TIAMARIA | Spanish for "Auntie Mary", a liqueur made from coffee beans |
| CUP | Here's an eye-opener: Palm civet coffee (also known as "kopi luwak"), which is made from coffee beans digested by an Asian cat-like animal, sells for $35 to $100 per ___ |
| CODEINE | Name a white, crystalline, bitter alkaloid, obtained from opium (7) |
| NICOTINE | Alkaloid is not nice, I decide (8) |
| OLIVES | I solve the manner in which oil is obtained from them (6) |
| SAGO | Which edible starch, used in puddings, is obtained from the palm? (4) |
| CURDS | Which substance is obtained from milk, for making into cheese (5) |
| RESIN | Which sticky flammable substance is obtained from trees? (5) |
| SEDER | Ritual in which bitter herbs are dipped |
| ISTLE | Plant fibre that is obtained from agave and is used in making carpets and cord? (5) |
| BULL | Tripe is obtained from bovine |
| CHRYSANTHEMUM | Pyrethrum is obtained from this plant genus - my anthers much spoilt (13) |
| BACON | This is obtained from the pig |