| LONDONGAZETTE | Which English official government journal was founded in 1665, published in London and contained gov |
| GAZETTES | What are official government journals (8) |
| DRURYLANE | London playhouse that began life as the Theatre Royal in which Nell Gwyn made her debut in 1665 (5,4 |
| ANNE | Queen born in St James's Palace in 1665, portrayed in the film The Favourite by Olivia Colman (4) |
| GREATPLAGUE | Event that struck London in 1665-66 |
| EYAM | Derbyshire village that voluntarily quarantined after the bubonic plague struck in 1665 (4) |
| CELL | Word coined by Robert Hooke in 1665 for a basic unit of life (4) |
| EEJIT | Fool in Dublin and in Rome holds back the speaker in London and Paris (5) |
| BARNES | Wayne, English official who refereed rugby union's World Cup final in 2023 (6) |
| PLAGUE | Epidemic (the "Great" one being in 1665) (6) |
| HIGHWAYCODE | In Britain, an official government booklet giving guidance to users of public roads (7,4) |
| ERECTOR | Muscle displayed by English official in Scottish university |
| SHAMANS | Medicine men pretended was unopened and contained (7) |
| NIGHTLIFE | In search of this? Hit Isabel in London and Public in New York |
| THOMASDEKKER | English poet and dramatist whose works include the plays Match Me in London and The Shoemaker's Holiday |
| TRANSFEREE | Footballer leaving has answer for English official after end of tournament |
| DECONTAMINATED | When tamed and contained, it turned out to be pollution free (14) |
| EVELYN | Author of a posthumously published diary describing events of 1665-6 including the Great Plague and the Great Fire of London (6) |
| BAKEWELL | Joan -, broadcaster and official government champion of the elderly (8) |
| HOOKE | English scientist who coined the term "cell" in his 1665 work "Micrographia" |