| UPSELL | What the clues for 4-, 8-, 10-, 28- and 39-Down are trying to do, and what their answers feature |
| CORLEONE | Old part of Spain in centre - and central part for 4 (8) |
| OUTOFORDERSIGNS | Some bathroom postings ... or what the clues to 16-, 21-, 46- and 59-Across are? |
| REPLY | Synonym of a word in the clue for 4-Down / Response |
| OLIVERTWIST | Dickens character (and a hint to what the *clue answers might have in common) |
| PIECEOFCAKE | Simple thing to do ... and what each starred clue's answer ends with? |
| AFORESAID | A clue for 4 mentioned previously? (9) |
| BUILDCHARACTER | What doing something difficult is said to do-and what you'll have done when you complete the answer at 124-Across |
| STANDIN | With 54-Across, what a bad school child may be told to do ... and what is depicted by this puzzle's circled letters |
| TRAP | Deceive by putting the same clue for 4-Down and 8-Across, for instance |
| BREAKASTORY | What an investigative journalist might do, and what the answers to the starred clues literally do |
| SOLVE | What you are trying to do |
| OSTEOPATHS | We may feel in our bones they are trying to do us good (10) |
| ABSOLVED | What you are trying to do amid bad working is excused |
| CHANGECOLOR | What autumn leaves do, and what five letters do in the answer to each starred clue |
| RUCK | In rugby union, a group of players who are trying to get the ball while it is on the ground (4) |
| DIVORCEBILL | What Hillary didn't do, and what 9 19D insists he doesn't have? (7,4) |
| UNCLES | Point to the clues for the male members of the family (6) |
| PUPATE | What the larva did and what the young dog consumed (6) |
| VACCINE | "Researchers around the world are trying to develop a(n) ... against the virus" |