| OCCIDENT | What is the Western Hemisphere known as (8) |
| LUPUS | Constellation in the southern hemisphere known as the Wolf (5) |
| NATO | What is the Western defence alliance founded in 1949? (inits)(1,1,1,1) |
| NEWWORLD | The Americas; the Western hemisphere (3,5) |
| AMERICAS | Much of the Western Hemisphere, with 'the' |
| NORTHAMERICA | Third largest of the world's continents in the present day, lying for the most part between the Arctic Circle and the Tropic of Cancer in the Western Hemisphere. (5,7) |
| OPOSSUMS | Most prevalent Western Hemisphere marsupials |
| SAOPAULO | Most populous Western Hemisphere city |
| TITICACA | Western Hemisphere's highest lake |
| GREATSALT | Largest saltwater lake in the Western Hemisphere, it lies in the northern part of the U.S. state of Utah (5,4) |
| ACONCAGUA | Mountain in the Andes, highest peak in the western hemisphere (9) |
| UTAH | Home of the largest saltwater lake in the Western Hemisphere |
| PERU | Home of the oldest university in the Western Hemisphere (founded in 1551) |
| CNTOWER | Toronto landmark that's the tallest free-standing structure in the Western Hemisphere |
| DEATH | Arid desert basin in California and Nevada that includes the lowest point below sea level in the Western Hemisphere (5,6) |
| VALLEY | Arid desert basin in California and Nevada that includes the lowest point below sea level in the Western Hemisphere (5,6) |
| FIDELCASTRO | Who turned his country into the first communist state in the Western Hemisphere? (5,6) |
| HAITI | First independent black nation in the Western Hemisphere, 1804 |
| LATINAMERICAN | Like much of the Western Hemisphere |
| CONDOR | Largest flying land bird in the Western Hemisphere |