| SEMAGLUTIDE | What drug was approved for use by the Scottish Medicines Consortium for weight loss in October? (11) |
| MAKEBOTHENDSMEET | The Channel Tunnel consortium, for example, had to stay solvent |
| NIKOLATESLA | Croatia was approved this month as the 20th nation to adopt the euro as its currency; what Croatian-born inventor was played by Ethan Hawke in a 2020 biopic? |
| GOLDENBOUGH | 'The ------ ', 1890 work by the Scottish anthropologist Sir James George Frazer subtitled A Study In Magic And Religion (6,5) |
| STONECUTTER | Machine responsible for weight loss? (11) |
| WENTTHROUGH | Looked at page by page and it was approved of (4,7) |
| EDENPROJECT | Green tourist attraction recently approved for Dundee (4,7) |
| EXPLOSIVE | Gunpowder, in use by the 9th century in China and the 13th century in the West, was the first known |
| TREAD | "Don't ___ on me" (slogan whose Wikipedia page has sections for "Use by the right," "Use by the left," and "Use in a terrorist act") |
| MODFESTIVAL | What National week is run from 10-16 October? (3-8) |
| SHERMAN | Name given to the Medium Tank M4, the primary tank produced by the US for use by the Allies during World War II (7) |
| CHOIRMASTER | Church maestro I played with close to October? |
| LEACH | Who took most wickets for England in the three-test series versus Pakistan in October? (4,5) |
| JACK | Who took most wickets for England in the three-test series versus Pakistan in October? (4,5) |
| DARK | What type of oxygen was found on the seafloor by the Scottish Association for Marine Science? (4) |
| DIET | From the Greek for "a way of life", the food one habitually eats; or, a regime designed for weight loss (4) |
| AIRPLANE | What Orville Wright publicly tested on July 27, 1909, for use by the U.S. Army, thus marking its first military application |
| PRESBYTERY | The part of a cathedral or church reserved for use by the clergy (10) |
| LIONS | What animals cast in bronze arrived in Edinburgh in October? (5) |
| HOZIER | Which Irish singer's debut album went to number 2 in the US charts in October? (6) |