| PRECIOUSMETALS | What are substances such as gold, silver and platinum? (8,6) |
| METALLURGY | The scientific study of the properties and uses of hard substances such as gold and iron (10) |
| DYES | What are substances used to colour fabrics? (4) |
| ELEMENTS | What are substances in the periodic table? (8) |
| METALS | Silver and platinum, say (6) |
| CONDIMENTS | Substances such as salt and mustard that are used to flavour food (10) |
| CULTUREMEDIA | Substances such as agar gel, as used in Petri dishes |
| INERTGAS | Group of non-reactive substances such as neon and argon (5,3) |
| BASES | Substances such as ammonia and sodium hydroxide |
| ENZYMES | Substances such as amylase and pepsin |
| CRYSTALLOGRAPHY | Science concerned with the structure of solid substances such as quartz, whose atoms are arranged in a definite pattern (5) |
| SPIRITS | Alcohol denatured by the addition of poisonous substances such as methanol, used as a fuel, solvent etc. (10,7) |
| METHYLATED | Alcohol denatured by the addition of poisonous substances such as methanol, used as a fuel, solvent etc. (10,7) |
| SPICES | Substances such as cumin, cloves, paprika, cinnamon, cardamom etc (6) |
| PESTLE | Club-shaped implement used to grind substances such as garlic in a mortar. (6) |
| ACIDITY | Level of acid in substances such as water, soil or wine (7) |
| UMAMI | The taste of substances such as monosodium glutamate (5) |
| SNIFFERDOG | Canine trained to detect substances such as explosives or drugs (7,3) |
| MODELLER | One who makes figures or objects out of substances such as clay or wood (8) |
| ASSAYERS | People who analyse substances such as metal (8) |