| NEOPETS | Virtual animals in an early-two-thousands fad |
| SARS | Disease in an early-two-thousands outbreak, familiarly |
| NEOPET | Virtual animal in an early 2000s fad |
| JOHNDODDS | Australian who helped develop an early two-stroke GP machine for Konig, then raced through most of the 1970s for yamaha. (4,5) |
| MURSE | Man bag, in early-two-thousands slang |
| PIMPED | Souped up, as one's ride, in early-two-thousands slang |
| MOESHA | TV daughter of Frank Mitchell, in the nineties and early two-thousands |
| AOL | Co. involved in a major merger of the early two-thousands |
| TECHBUBBLE | It burst in the early two-thousands and sent dot-com stocks tumbling |
| NASCARDADS | Largely white and rural set of voters, in early-two-thousands political analysis |
| THEOC | Early-two-thousands drama with the theme song "California" |
| BOHO | ___-chic (hippie-inspired fashion trend of the early two-thousands) |
| HOMESTAR | ___ Runner (early-two-thousands animated Web series) |
| PHAT | Baby ___ (prominent fashion brand of the early two-thousands) |
| EPIGRAM | The last two animals in an ingenious litttle poem |
| CURIO | Whether an antique musical barrel organ with a peculiar mechanism, a bizarre geological specimen, a butterfly in a glass case or a taxidermised animal in an unusual pose, it is an objet or novelty, na |
| COUNTINGSHEEP | Enumerating imaginary animals in an attempt to overcome insomnia (8,5) |
| CLAW | Grabber of stuffed animals in an arcade |
| TORTOISE | Animal in an Aesop fable (8) |
| TOMCAT | Yowling animal in an alley |
