| ILL | Villain a little unwell (3) |
| BELOWPAR | A little unwell, as an eagle is? (5,3) |
| HUTU | Member of a Bantu-speaking people in shed, a little unwell (4) |
| MEDIUMRARE | A little unwell? |
| ELLIS | Man giving his name to New York island a little unwell, I sense (5) |
| CRUELLADEVIL | Note in villainous villain, a villain! (7,2,3) |
| BADEGG | Villain, a stinker? (3,3) |
| CICADA | Spies catching villain, a six-footer (6) |
| BOOTEE | Greet the villain - a shirty type with childish footwear (6) |
| WICKHAM | Pride and Prejudice's villain; a military officer who romances the youngest Bennet sister (7) |
| ANTIHERO | Novel's villain, a bad boy of ancient Rome inspiring revolutionary best-seller (8) |
| OGRES | Great villains, a bit retrogressive (5) |
| PIRATES | Villains a priest reformed (7) |
| AIL | Feel unwell, just a little off |
| GUN | Feeling unwell, being pierced by weapon (3) |
| OFF | Feeling unwell on holiday (3) |
| ALE | Drink and feel unwell, so they say (3) |
| FLU | Feel low and unwell initially, due to this? (3) |
| BAD | Unwell; rotten (3) |
| SIC | Just so unwell, by the sound of it (3) |
