| MIXEDREACTION | Variety of responses, or a hint to the word scrambled within 20-, 28- and 47-Across |
| AYES | Positive responses, or just one? |
| REACT | Show a response or a reaction to something. |
| ROGER | A radio response or a James Bond portrayer |
| KEYCHANGE | A to B, for one ... or a hint to the word scrambled within each starred clue's answer |
| PROTEINSHAKE | Healthy drink, and a hint to the word scrambled within each starred clue's answer |
| FILMADAPTATIONS | Novel forms for novels, and a clue to the word scrambled within each starred answer |
| GENDERFLUID | Not conforming to male or female stereotypes, and a hint to the word scrambled within 17-, 27- and 44- Across |
| RECYCLINGCENTER | Destination for bottles and cans, and a hint to the word scrambled in each starred clue's answer |
| SECONDSHIFT | Afternoon-to-evening work period, typically ... and a hint to the word scrambled in each starred clue's answer |
| BADROMANCE | 2009 hit with the lyric "I want your love," or a hint to the word scrambled in each starred clue's answer |
| STIRDEBATE | Engender public controversy, or a hint to the word scrambled in each starred clue's answer |
| SPINDOCTOR | Crafty press agent, or a hint to the word scrambled in each starred clue's answer |
| FIDGETSPINNER | Twirling fad toy, and a hint to the word scrambled within 19-, 25- and 43-Across |
| ORGINTRANSPLANTS | Changes of heart, say? (Theme hint: The word "tarragon" is scrambled within this answer) |
| NEWBEGINNINGS | What January 1 brings for many people, and a hint to the first letters of 20-, 28- and 47-Across |
| DOUBLEPARKED | Like a delivery truck blocking your car, maybe ... and a hint to 20-, 28- and 47-Across |
| RETORTS | The sort of responses one might expect in a laboratory |
| REACTIONS | They're the sort of responses one might expect from that coster, Ian |
| MOTHEATEN | Shabby playhouse right to be got rid of within twenty-four hours |
