| TERESHKOVA | Valentina -; cosmonaut who was the first woman in space (10) |
| YURIGAGARIN | The cosmonaut who was the first man in space (4,7) |
| GAGARIN | Cosmonaut who was the first human to travel in space, Yuri ... |
| LEONOV | Alexei -; cosmonaut who was the first human to walk in space (6) |
| ELLENOCHOA | First Hispanic woman in space, aboard the space shuttle Discovery in 1993: 2 wds. |
| CHALLENGER | Space shuttle in which Sally Ride became the first American woman in space (June 19, 1983) |
| MAEJEMISON | First African-American woman in space, aboard the space shuttle Endeavour in 1992: 2 wds. |
| USSR | Nation who put the first woman in space |
| TITOV | Gherman ___, cosmonaut who was the second human to orbit the earth |
| ALEXEILEONOV | Soviet cosmonaut who was the first human to conduct a spacewalk (6,6) |
| VALIDATING | Confirming Valentina and I ... going steady! (10) |
| COSMONAUTS | Russian astronauts such as Yuri Gagarin and Valentina Tereshkova |
| MOLLYKOOL | Captain ___ ___ (b.1916 - d.2009 ...Canadian who became, in 1939, the first woman in North America to attain the certification of 'Master of a Cargo Steamship in the Home-trade') |
| SALLYRIDE | America's first woman in space |
| RB | Canada's first woman in space, initials (2) |
| ROBERTA | ___ Bondar, Canada's first woman in space |
| USA | Sally Ride was 1st woman in space for this country |
| EVE | Who is the first woman in the Bible? (3) |
| RIDE | First woman in space |
| ANDERSON | Elizabeth Garrett _ _ _ _ _ _ _ _ , the first woman in the UK to qualify as a professional doctor in 1865 (8) |