| SIDEEFFECT | Unwanted action (of a drug) (4,6) |
| SIDEEFFECTS | Secondary actions (of a drug) (4,7) |
| CENTRIFUGE | A rotating machine that separates liquids from solids by the action of a type of force (10) |
| HOMEOPATHY | Method of treating disease by the use of small amounts of a drug that, in healthy persons, produces symptoms similar to those of the disease being treated |
| ARMAGEDDON | Final action of a jolly old chap |
| STALINGRAD | Last daring action of a German advance (10) |
| DERAILMENT | The action of a train or tram leaving its tracks accidentally (10) |
| BLOODMONEY | Part of a drug lord's income, maybe |
| QUINAQUINA | Cinchona bark, source of a drug used to treat malaria |
| COCAINISED | Adam's boy is found in school, under the influence of a drug (10) |
| COASTGUARD | One on the lookout for smugglers of a drug at sea on cruise? (10) |
| SHOT | A gun blast synonymous with conjecture, guesswork or speculation when figuratively undertaken in the dark; otherwise, a dram of spirits; a jab of a drug; or, a serving of espresso (4) |
| UNCLIP | Word used to describe the action of a cyclist when releasing a cleat from a pedal during a pause or dismount (6) |
| LEACH | Purging a soluble matter out of something by the action of a percolating fluid - such as fertiliser out of the soil caused by heavy rain (5) |
| TOLERANCE | Ability of the body to resist the action of a poison, endure large doses of active drugs etc. ( 9) |
| RICOCHET | Action of a bullet rebounding from a surface, usually with a whining or zipping sound (8) |
| PLACEBO | A substance with no effect given to a patient by a doctor instead of a drug (7) |
| PRESCRIPTION | Written instruction from a doctor or dentist to a pharmacist stating the form and dosage of a drug to be issued to a patient (12) |
| DOSE | A prescribed quantity of a drug; or, a bout of something unpleasant (4) |
| KNEADING | Requiring, by the sound of it, the action of a masseur (8) |
