| DONAMECHE | US actor and comedian, born 1908 in Wisconsin whose career spanned nearly 60 years (3,6) |
| DAYS | Soap for nearly 60 years, familiarly |
| ERA | She's reigned for nearly 60 years, a long period (3) |
| GARBAGE | Alternative rock band formed in Wisconsin whose best-selling single is 1996's Stupid Girl |
| EAU | ___ Claire (city in Wisconsin whose name is French for clear water) |
| SINGER | ___ Building, company headquarters erected in 1908 in New York City, at the time the tallest building in the world |
| EHRLICH | German physician, co-recipient of a Nobel Prize in 1908 in recognition of his work on immunity (7) |
| HELIX | He's nearly 60 with constant wind (5) |
| DANNYKAYE | U.S. actor and comedian born in 1911 noted for his patter songs (5,4) |
| VICREEVES | Actor and comedian born James Moir (3,6) |
| NICHOLSON | Hollywood star with a career spanning over 60 years, Jack ... (9) |
| ALDA | US actor and comedian born Alphonso Joseph D'Abruzzo in 1936 (4) |
| ALAN | US actor and comedian born Alphonso Joseph D'Abruzzo in 1936 (4) |
| FORMBY | George, English actor and comedian born in Wigan in 1904 noted for playing the ukulele (6) |
| DEANMARTIN | US singer, actor and comedian born Dino Paul Crocetti in 1917 (4,6) |
| BOBBYDAVRO | Actor and comedian born Robert Nankeville in 1958 and noted for his pantomime appearances (5,5) |
| BERNARDCRIBBINS | English actor and comedian born in 1928 who narrated the children's TV series The Wombles (7,8) |
| NORMAN | ____ Wisdom, English actor and comedian born in 1915 noted for his slapstick comedy (6) |
| JOHNBIRD | English late actor and comedian born in 1936 noted for his satirical sketches (4,4) |
| EVEARDEN | Mildred Pierce and Stage Door actress whose career spanned six decades |
