| MEKONG | Trans-boundary river in East and Southeast Asia (6) |
| GANGES | Trans-boundary river of Asia which flows through India and Bangladesh (6) |
| SEVERN | A river in East Wales and West England, flowing through Shrewsbury, Worcester and Gloucester (6) |
| SHEOAK | Another name for the tree casuarina of Australia and SE Asia (3-3) |
| RANGED | River in East - that's crossed by crews (6) |
| RANGES | River in East - that's crossed by crews (6) |
| SEAWAY | Main route, for example, takes in east and west primarily (6) |
| ESTATE | Property in East and West Bengal perhaps (6) |
| SHTETL | Name for a Jewish village or settlement in east and central Europe before the Holocaust (6) |
| BROADS | The ---, a group of shallow navigable lakes, connected by a network of rivers in east England (6) |
| ALTAIC | Family of languages of Asia and SE Europe now discredited (6) |
| UBANGI | Congo boundary river |
| MARNE | French river that is a right tributary of the Seine in the area east and southeast of Paris |
| ENTHUSE | Show keenness to hunt, maybe, in the east and southeast (7) |
| IORA | Related to the fairy bluebird, a species of yellow and green songbird found in India and southeast Asia (4) |
| FISHING | The moniker for this smallish tropical cat found in India and Southeast Asia, characterized by dark spots and streaks, that's known for scooping its prey out of the water. |
| TAPIR | Mammal of South and Central America and southeast Asia with an elongated snout |
| LORIKEET | A small, brightly coloured parrot found in Australia and southeast Asia (8) |
| MUNTJAC | Small deer native to South Asia and Southeast Asia (7) |
| ESE | The compass point midway between east and southeast. |