| CYANIDE | Toxic chemical compound first isolated from Prussian blue in 1782 and present in high quantities in the stones and seeds of fruits such as apples, apricots and peaches (7) |
| MSG | Compound first isolated from seaweed broth |
| VANBUREN | Martin, U.S. president of Dutch descent born in 1782 and nicknamed The Little Magician (3,5) |
| ETHANE | Chemical compound first synthesised by Faraday in 1834 |
| IRON | An element created by nucleosynthesis and present in the body's haemoglobin; or, an appliance used for pressing laundered linen (4) |
| ANTIDOTE | Prussian blue, for thallium poisoning |
| PCBS | Toxic chemical compounds in industrial waste, briefly |
| PURPLEHEART | Oldest US military decoration still in use, first awarded by George Washington in 1782 (6,5) |
| SORBITOL | Sweet crystalline compound first discovered in the berries of the mountain ash tree (Sorbus aucuparia) in 1872, used in foods as the additive E420 (8) |
| ACETATE | Synthetic compound, first prepared in 1865, used in the manufacture of textile fibres, photographic films, varnishes etc. (9,7) |
| CELLULOSE | Synthetic compound, first prepared in 1865, used in the manufacture of textile fibres, photographic films, varnishes etc. (9,7) |
| ROCKINGHAM | 2nd Marquis of ?, prime minister from 1765-66 and in 1782 |
| FALCONET | Artist who completed the Bronze Horseman in St Petersburg in 1782 (8) |
| FOX | Charles ?, British Whig statesman who served for three periods as Foreign Secretary in 1782, 1783 and 1806 |
| POTASSIUM | Occurring in seawater and first isolated by Sir Humphry Davy in 1807, an element that derives its symbol "K" from the Latin "kalium" (9) |
| BALDEAGLE | This bird may have numbered in the hundreds of thousands when it was declared the American national bird in 1782, but its numbers steadily declined over the next two centuries, owing primarily to huma |
| HOME | Major governmental department of the UK, brought into being in 1782 (4,6) |
| OFFICE | Major governmental department of the UK, brought into being in 1782 (4,6) |
| ARGON | First isolated in 1894 by Lord Rayleigh and Sir William Ramsay, a noble gas, atomic number 18 (5) |
| NITROGEN | Chemical element, atomic number 7, first isolated by Daniel Rutherford in 1772 (8) |
