| INHER | Toni Collette comedy drama about two very different sisters, ___ Shoes |
| ABOY | Hugh Grant and Toni Collette comedy-drama, About ... (1,3) |
| JEKYLLANDHYDE | A person with two very different sides to their personality (6,3,4) |
| BONES | Nickname for two very different TV doctors |
| TEENYBOPPER | Young trendy getting two very different hats from Spooner? |
| HER | Toni Collette comedy drama, In _ Shoes (3) |
| SHOES | Cameron Diaz and Toni Collette comedy drama, In Her ___ (5) |
| UNITED | Toni Collette comedy drama, ... States of Tara (6) |
| OFTARA | Toni Collette comedy, United States ... (2,4) |
| VIDA | TV drama about two Mexican-American sisters ended (4) |
| SUPERNATURAL | Long-running drama about two monster-hunting brothers |
| MALLARD | Complicated drama about two lakes and a duck (7) |
| ELNORTE | 1983 Gregory Nava drama about two Guatemalan youths fleeing their country's civil war |
| IVORYTOWER | One or two, very unusually, found in academics' dwelling (5,5) |
| GOGANDMAGOG | A good three gallons man's drunk - or two very large ones |
| BUSHBABY | African primate, one of two very young ones destined to be president? (8) |
| BEHAVE | Two very common verbs cause no trouble |
| OLIVE | _ and Mabel are the stars of Andrew Cotter's Two Very Good Dogs (5) |
| GEMINI | Two very similar, but a precious stone in one (6) |
| PRAM | ___ face, BBC Three comedy drama about teenage pregnancy (4) |