| PEAKE | Tim -; the first British ESA astronaut to visit the International Space Station (5) |
| TIMPEAKE | The first British astronaut to visit the International Space Station with the European Space Agency (3,5) |
| ENDEAVOUR | First space shuttle to visit the International Space Station (9) |
| ORBIT | Travel around the Earth like the International Space Station |
| ALAIN | Michelin-starred chef Ducasse who sent gourmet meals to astronauts on the International Space Station |
| GLENN | John, the first U.S. astronaut to orbit the earth who later became a senator (5) |
| SOYUZ | Vehicle visiting the International Space Station |
| ALLEN | Tim 'The Tool Man' Taylor in Home Improvement, Tim ... (5) |
| JUICE | From French for "broth", the extract of fruits or vegetables; vitality or vigour; an informal term for alcohol, electricity or fuel; or, the name of an ESA Jupiter mission (5) |
| FINNS | Jean Sibelius and Esa-Pekka Salonen |
| COLUMBUS | The European Space Agency's programme contributing to the International Space Station |
| SHEPHERD | Bill, the first commander of the international space station |
| INORBIT | Life ___ ___: The International Space Station (Current exhibition at the Canada Aviation and Space Museum) |
| SATELLITE | Device used to capture images of various regions of the world from the International Space Station. (9) |
| SUNITA | Astronaut Williams, who described the International Space Station as her "happy place" |
| MACHINE | In 2015, what did Italian astronaut Samantha Cristoforetti install in the International Space Station? (6,7) |
| COFFEE | In 2015, what did Italian astronaut Samantha Cristoforetti install in the International Space Station? (6,7) |
| EXPEDITIONONE | First extended stay on the International Space Station |
| ANT | Insect once brought to the International Space Station |
| SPACEX | Private aerospace company that welcomed Nasa astronauts Sunita Williams and Butch Wilmore to the International Space Station. (6) |
