| NATUROPATHY | This word, meaning treatment and cures using natural remedies, was first coined more than 100 years |
| CHINESEHERBALMEDICINE | System using natural remedies |
| ECRU | Cure using natural linen |
| DRYSALT | Doctor lays out basis of treatment and cure (3-4) |
| BRONTOSAURUS | The name of a genus of famous sauropod dinosaurs that was reinstated in 2015 after being included in the genus Apatosaurus for more than 100 years. |
| FUMANCHU | Author Sax Rohmer introduced which villain in 1912, the character featuring in books, films, television, radio, and comic strips for more than 100 years? (2,6) |
| RAPIER | Ransomes & _ _ _ _ _ _ - Suffolkbased manufacturer of railway equipment for more than 100 years (6) |
| SCOW | Type of boat lodged in Niagara Falls for more than 100 years |
| ANTIBODY | This word, meaning a blood protein which reacts against foreign substances, was first used in 1901 |
| SCOUTMOVEMENT | Reject motion that's more than 100 years old (5,8) |
| ELOI | Wells created them more than 100 years ago |
| LEMONBALM | Often planted near apiaries and used in herb pillows and natural remedies, flagrant perennial whose genus name Melissa derives from the Greek word for honeybee (5,4) |
| ADDICT | A drug-dependent person became known by this word, first coined in 1909 |
| ADDICTS | Drug-dependent people became known by this word, first coined in 1909 |
| FADO | Irish folk tales often begin with this word, meaning "long ago". (4) |
| ADULT | This word meaning mature became a synonym for pornographic in connection with films or bookstores |
| FUNGI | Plants such as mushrooms and toadstools, Mallorca has more than 100 edible varieties --and many more that are wiser to avoid (5) |
| THAMES | Town which, in 1868, was New Zealand's largest, with more than 100 hotels and three theatres (6) |
| ALTEREGO | Term first coined by Cicero, meaning "a second self, a trusted friend (5,3) |
| VELOCIPEDE | Term, first coined in 1818, for any human-powered land vehicle with one or more wheels, most commonly the bicycle |