| NONO | This is impossible without oxygen (2-2) |
| IMHOOKED | "This is impossible to put down!" |
| DORY | Fish - without water, without oxygen (4) |
| TRAP | Situation in which it is impossible to escape |
| WISE | "It is impossible to love and to be ___": Francis Bacon |
| OINK | E.g. Napoleon's comment suggesting why tattoo is impossible |
| FRAY | Become strained from sudden attack without oxygen |
| MIST | Result of condensation, being damp, without oxygen (4) |
| ELMS | Troublesome moles without oxygen in the trees (4) |
| LOOP | Circuit cut without oxygen (4) |
| VINE | Climber to struggle without oxygen ultimately (4) |
| POOH | Kids' character who says "People say nothing is impossible, but I do nothing every day" |
| NOCANDO | Agreement about prison? Nothing is impossible (2,3,2) |
| ANAEROBIC | Be in a car suffering without oxygen? Without oxygen! (9) |
| ENDOFTHEROAD | Point beyond which survival is impossible (3,2,3,4) |
| FLATOUT | Residential accommodation is impossible this quickly (4,3) |
| STUCKON | Crazy about, is impossible to shake off (5,2) |
| THERESNOSAYING | Being silent it is impossible to guess (6,2,6) |
| TELLING | It is impossible to know what will happen, there is no ___ |
| NOTON | Going to and fro is impossible (3,2) |
