| JAMESAGARFIELD | The second of four US President to be assassinated, his fatal injuries spurred the invention of a metal detector and air conditioner |
| OBAMA | One of four US presidents to win a Nobel Peace Prize |
| DARLINGNIKKI | Controversial song by Prince that spurred the creation of parental advisory stickers on albums (1816) |
| BETTYCROCKER | Which woman, one of the best-known cooks in the US, was only the invention of a flour company? (5,7) |
| COINAGE | The act of striking metal money; the bits, pieces or specie made; or, the invention of a neologism (7) |
| WISCONSIN | Second of four US states that are 8-Down letters long |
| EGO | Source of a "me, me, me" trip |
| SELFCARE | Focus of a "me day" |
| DIA | Small fraction of a mes |
| BATESOFBURDEN | Dropout's assessment of a Maine college? |
| ABE | Nickname of the first US president to be assassinated |
| BILLCLINTON | The only US President to be a Rhodes Scholar, and one of two to be impeached by Congress |
| ABRAHAM | First US President to be assassinated, ... Lincoln |
| RONALDWREAGAN | The oldest US President to be elected into office was known to stock jellybeans in the Oval Office |
| GARFIELD | Second president to be assassinated |
| DAVY | Cornish chemist whose invention of a firedamp safety lamp decreased the number of fatalities of miners and contributed to the progression of the industrialisation of Britain (4) |
| RUSHMORE | Gutzon Borglum was the architect of this large granite sculpture of four US presidents, Mount ... |
| MOUNTRUSHMORE | Where giant relief carvings of four US presidents are to be seen in South Dakota (5,8) |
| VALKYRIES | Ride of the _, second of four operas in Wagner's The Ring of the Nibeiungs (9) |
| FDR | Initials of the only US president to be elected four times |
