| SOLE | The only one to lose out (4) |
| PLUM | The Norfolk Cake Company in Downham Market is proud that their Norfolk Cake is one of the only ones to actually contain this fruit, rather than the currant and raisin alternative that many other brand |
| FADE | A deficiency, primarily in iron, may cause one to lose strength (4) |
| MIND | Terrible thing for one to lose or waste |
| TEMPLE | Who features three times on the Set Pepper's album cover and was the only one to ask to hear the album before giving consent to use her image? (7,6) |
| SHIRLEY | Who features three times on the Set Pepper's album cover and was the only one to ask to hear the album before giving consent to use her image? (7,6) |
| TAFT | *Only one to hold position in Executive and Judicial branches |
| DESPERADO | The Eagles' second album and the only one to feature the band on the cover |
| LEE | Of all the actors in The Lord of the Rings films, who is the only one to have met JRR Tolkien? (11,3) |
| CHRISTOPHER | Of all the actors in The Lord of the Rings films, who is the only one to have met JRR Tolkien? (11,3) |
| SLOE | Lose out on the gin! (4) |
| LOVES | Figure to lose out badly in one's affairs (5) |
| MISSTHEBUS | Wife cuddles Beth, upset to lose out (4,3,3) |
| WIGGLING | Moving first to lose out would lead to rebuke (8) |
| ITOO | "You're not the only one to..." |
| SOCLE | Foot of column, the only one to include its top (5) |
| RECEIVEAPULITZERPRIZE | JFK: The only one to ___ |
| GRAPHICNOVEL | "Maus" is the only one to win a Pulitzer Prize (1992) |
| RASH | Authors lose out in some spots (4) |
| CUPS | Beakers, in closeups, lose out (4) |
