| HUBBLE | The first sophisticated orbital optical observatory. It was launched by the U.S. space shuttle Discovery on April 25, 1990. Among its many discoveries, it was also used to discover Hydra and Nix, two |
| MIR | It was launched by the Soviets in 1986 |
| TIROS | Abbreviation for the series of television and infrared observation meteorological satellites launched by the U.S. starting in 1960. (5) |
| ARIEL | Series of six artificial satellites launched by the U.S. from 1962 to 1979 (5) |
| HUBBLETELESCOPE | It was launched by "Discovery" |
| CHALLENGER | U.S. space shuttle orbiter that disintegrated after launch in 1986 (10) |
| ALA | State that's home to the U.S. Space & Rocket Center: Abbr. |
| NASA | Hit song by Ariana Grande from her 2019 album whose title is named after the U.S. space agency |
| MARINER | The name for any of a series of ten uncrewed U.S. space probes sent to the vicinities of Venus, Mars, and Mercury between 1962 and 1973. The first was launched July 22, 1962, but was destroyed shortly |
| SPUTNIK | Name for a series of space missions launched by the Soviet Union, the first of which launched the first man-made object to orbit the Earth |
| GPS | Network operated by the U.S. Space Force |
| CAPECANAVERAL | Site in Florida used for launches in the U.S. space programme (4,9) |
| SKYLAB | The first U.S. space station, launched into Earth orbit on May 14, 1973. In July 1979 it entered the atmosphere, broke up, and scattered debris over the southeastern Indian Ocean and western Australia |
| PIONEER | Name for any of the first series of uncrewed U.S. space probes designed chiefly for interplanetary study that were launched between 1958 and 1973. The 10th probe in this series became, in June 1983, t |
| EUCLID | Space telescope launched by the European Space Agency in July 2023 to study dark matter and dark energy (6) |
| TEEN | It was programmed on screen to be launched by the 16th, in '66. (4,4) |
| STAR | It was programmed on screen to be launched by the 16th, in '66. (4,4) |
| BRITANNIA | This royal yacht was launched by Queen Elizabeth on April 16, 1953 |
| SURVEYOR | Any of a series of seven uncrewed U.S. space probes sent to the Moon between 1966 and 1968 to photograph and study the lunar surface. (8) |
| MSN | It was launched on the same day as Windows 95 |