| SYSTOLIC | The aspect of blood pressure that is costly |
| FLUCTUATES | "But nowadays, it's my blood pressure that ___" |
| FACETIOUS | The aspect promises to be inappropriately amusing (9) |
| ECOCIDE | Destruction of the aspects of the environment that support life (7) |
| SCHEME | Astrological representation of the aspects of the planets; a secret plot; or a planned combination of |
| PIEBALD | Pressure that is detrimental around large type of horse (7) |
| APPLEPIE | Tech company pressure that is producing such order (5-3) |
| UNDUE | Blowgun duellists have pressure that is uncalled for (5) |
| SAGGING | Giving way to pressure that is superior (7) |
| FISHPIE | Pressure that is on search for food (4,3) |
| CUFFS | Ends of sleeves; parts of gloves or gauntlets covering the wrists; or, the inflatable armbands of blood pressure monitors (5) |
| RENIN | Protein and enzyme secreted by the kidneys, a central hormone in the control of blood pressure (5) |
| ATMOSPHERE | A unit of pressure equivalent to the pressure that will support a column of mercury 760mm high at 0 degrees Celsius at sea level |
| PLASMA | Component of blood pressure lowered after some medical attention at first |
| ARBS | Class of blood pressure lowering meds, initially |
| TEACHER | It seems, sir, that a cuppa is costly on the Continent! (7) |
| RICH | Energy sourced from the German state is costly (4) |
| ALBERTACLIPPER | In Canada, an area of low pressure that forms in winter near the Rocky Mountains (7,7) |
| STEEPLE | Essayist's written about pressure that the church may be under |
| EASED | Relaxed the pressure that might be applied to a seed (5) |
