| FISHES | The ---, twelfth sign of the zodiac also called Pisces (6) |
| PISCES | The twelfth sign of the Zodiac (6) |
| CANCER | In astrology, the fourth sign of the zodiac, also called the Crab (6) |
| TAURUS | The second sign of the zodiac, also called the Bull (6) |
| GEMINI | The third sign of the zodiac, also called the Twins (6) |
| PISCEAN | Person born under the twelfth sign of the zodiac (7) |
| LIBRA | In astrology, the seventh sign of the zodiac, also called the Scales (5) |
| ARIES | The first sign of the zodiac, also called the Ram (5) |
| ALTAIR | The brightest star in the constellation of Aquila and the twelfth-brightest star in the night sky (6) |
| MUCKUP | Make a mess of Puck's anagram, putting the twelfth letter first (4,2) |
| EDICTS | It's the twelfth month when decrees are issued (6) |
| MATHIS | "The Twelfth of Never" singer Johnny |
| GROUSE | Likely to get shot after the twelfth complaint! (6) |
| SENIOR | Student in the twelfth grade |
| OLLYMURS | Runner-up in the sixth series of The X Factor who returned as co-host of the twelfth series (4,4) |
| OCTOBER | The twelfth of this month is the date of Columbus's landfall (7) |
| ADAR | In the Jewish calendar, the twelfth month of the ecclesiastical year (4) |
| ABZ | Member of the boy band Five who was runner-up on the twelfth series of Celebrity Big Brother (3) |
| INCH | Unit of length equal to the twelfth part of a foot; or, a unit of rainfall (4) |
| KEILLOR | Garrison who plays the Guy who works on the twelfth floor of the Acme Building |