| CHEWEDTHEFAT | Talked about, as one embarked on a high-cholesterol diet |
| STEAKFRIES | Part of a high-cholesterol meal, maybe |
| CRUISE | One embarked in old vessel for this voyage (6) |
| OLDIE | Low-cholesterol diet protects senior citizen |
| STYX | In which Susanne Wolff embarked on a one-woman solo sailing trip (4) |
| WATERS | Pink Floyd co-founder who embarked on a solo career in 1984 and since released albums including Radio K.A.O.S. and Amused to Death (6) |
| LUMLEY | Actress and presenter who embarked on a Trans-Siberian Adventure by train for a 2015 TV series (6, 6) |
| BEDMAKER | College cleaner embarked on a trip |
| DANCER | What Kate Ramsay wanted to be before she embarked on a career in education in Neighbours (6) |
| ABOARD | Embarked on (a ship) |
| HONEY | ___ Mitchell, has embarked on a relationship with Lola Pearce's ex Jay Brown in EastEnders (5) |
| WARBRIDES | Spouses of Canadian servicemen who embarked on a new life in Canada via Pier 21 in the 1940s: 2 wds. |
| MAIDENVOYAGE | Titanic embarked on its fateful one on April 10th, 1912: 2 wds. |
| YEARENDSAIL | Embarked on Dec. 31 (at a bargain price, too)? |
| TONKED | One hundred thousand embarked on vacation to get hammered |
| NIACIN | Vitamin often recommended as a supplement for patients with high cholesterol |
| FRANCE | On July 1, 1903, several dozen cyclists embarked on the first Tour de ___, which would become the most famous European bicycle race |
| GALLOPING | Having embarked on career without work is infuriating |
| YACHTED | Year 8 in Germany embarked on vacation, went sailing (7) |
| HEADEDOFF | Embarked on journey to deflect Edward from course (6,3) |
