| PHARMACEUTICALS | Susan, the agriculturist, makes you laugh out loud - it's the drugs! (15) |
| OPIATES | Poet is a mess: must be the drugs! (7) |
| VIAGRA | Sylvia gradually absorbed the drug! (6) |
| SITUATIONCOMEDY | After a job, retiring round the Med is something that makes you laugh (9,6) |
| THREETENTHSROCK | NBC show that received a Peabody "for creating television that laughs out loud at television" |
| FLOODSOFTEARS | For crying out loud, it's only the waterworks (6,2,5) |
| ICECREAM | The writer cries out loud, it's so cold! |
| ICING | When I sing out loud, it's sweet (5) |
| INGESTION | Joking out loud, it's charged with taking in (9) |
| NOSE | A clown is the goofy guy at the circus with the big, round ___ who won't be happy until he makes you laugh |
| TICKLER | He makes you laugh when the nit-picker loses the opener (7) |
| WEEPIE | For crying out loud, it's only a film of 'inch-eye' Private Eye perhaps from Spain (6) |
| NARNIA | Literary domain of Peter the Magnificent and Susan the Gentle |
| LENO | Jay who said "You can't stay mad at someone who makes you laugh" |
| CARTOON | Root about in the container and it makes you laugh (7) |
| TRIPOD | When you're wobbly and about to snap, it helps to take drugs ? lots of drugs! |
| ASHCROFT | Lead singer of The Verve, the band best-known for the singles Bitter Sweet Symphony and The Drugs Don't Work (8) |
| GUFFAW | Laugh out loud when half the guys waffle about getting rid of the French (6) |
| SAUL | Whom had you better call, should you be in the drugs business in Albuquerque? (4) |
| RETCH | "If a topic makes you [...] laugh, or sigh, or ____ - or react physically in any way - you have a winner" (Scott Adams, Dilbert cartoonist) |