| QUINTO | Surname of Zachary - Sylar in Heroes in the 2000s and Spock in Star Trek, 2009 (6) |
| JESSE | First name of Mr Metcalfe who played John Rowland in Desperate Housewives in the 2000s and performed as Astronaut on The Masked Dancer in 2022 (5) |
| ZACHARY | ------- Quinto, played evil Sylar in Heroes (7) |
| OBOES | Instruments played by Liang Wang and Sherry Sylar in the New York Philharmonic |
| MILLARDFILLMORE | ___ was the last US president from the Whig party, taking office after the death of Zachary Taylor in 1850 |
| FACE | Confront one of the heroes in The A-Team (4) |
| JOHNTHEBAPTIST | Son of Zachary and Elizabeth in the Bible (4,3,7) |
| MEDIEVALKNIGHTS | Spooner says, 'Neddy, evil mites were heroes in the Middle Ages' (8,7) |
| WHIG | Party of Zachary Taylor and William Henry Harrison |
| VULCAN | Spock in Star Trek had a father of this extraterrestrial race (6) |
| LARTER | Ali _ -, actress who played played dual roles of Niki Sanders and Tracy Strauss in Heroes (6) |
| MANY | "The needs of the ___ outweigh the needs of the few" (utilitarian sentiment expressed by Spock in "Star Trek II: The Wrath of Khan") |
| SCOTTY | Shipmate of Kirk and Spock |
| FANART | Pictures of Kirk and Spock kissing, e.g. |
| ALIENS | Mork and Spock, for two |
| HEROES | TV show with a villain named Sylar |
| ADRIAN | In Heroes, actor _ Pasdar was Nathan Petrelli. |
| CABBIE | Mohinder Suresh in "Heroes," for one |
| LOTTERY | Game show of the 2000s and 2010s, The National _: In It To Win It (7) |
| ERICBANA | Portrayer of Nero in "Star Trek" (2009) |
