| QUININE | Substance formerly used to treat malaria (7) |
| SHELLAC | Substance formerly used to make gramophone records |
| HALON | Substance formerly used to extinguish fires involving electronic equipment |
| ETHER | Word for clear upper air originally, later a rarefied substance formerly believed to permeate all space; or, a sweet-scented volatile liquid (5) |
| BUGLOSS | Wildflower formerly used to treat snake bites (6,7) |
| QUININES | Cinchona bark products used to treat malaria |
| QUINAQUINA | Cinchona bark, source of a drug used to treat malaria |
| TABOURS | Small drums formerly used to accompany oneself on a pipe. (7) |
| VIPERS | Wildflower formerly used to treat snake bites (6,7) |
| RATTLES | Chatterers; crackling noises of paper; dice-boxes; maracas, shakers or toys resembling thus; or, watchmens' instruments formerly used to produce whirring sounds (7) |
| CATCALL | A squeaking or wauling noisemaker formerly used to express disapproval in a theatre, thus a term for a boo, gibe, hiss, jeer or raspberry from a crowd or audience; or, a "swit swoo" sound (7) |
| CHAULMOOGRA | Tropical Asian tree whose seeds yield an oil formerly used to treat leprosy (11) |
| LAUDANUM | This solution of opium in alcohol was formerly used to treat pain (8) |
| EYEBRIGHT | Plant with small, white-and-purple, two-lipped flowers, formerly used to treat optical disorders (9) |
| GRAIN | Unit of mass equal to a seed of com; 1/4 of a carat formerly used to measure diamonds/pearls; or, a unit used to weigh archers' arrows (5) |
| LOUPES | French word formerly used to refer to imperfect precious stones, later to the small magnifying glasses of gemologists, jewellers, rock enthusiasts or watchmakers (6) |
| TARLATAN | Name, similar to that of Scottish plaid, for a type of stiffened muslin formerly used to add shape to ball-gowns, crinolines or dresses (8) |
| POMANDER | A ball or perforated container of mixed aromatic substances formerly carried as a supposed protection against infection |
| ASTROLABE | An instrument formerly used to make astronomical observations as an aid to navigation |
| LINSTOCK | Long staff to hold a lighted match, formerly used to fire cannons (8) |
