| MEET | Stand up to mixture of methadone and ecstasy (4,4-2) |
| HEADON | Stand up to mixture of methadone and ecstasy (4,4-2) |
| HONED | Mate got off methadone and improved (5) |
| TONICWATER | Mixer twice ran to mixture (5,5) |
| HEATHENDOM | Heroin and methadone scattered in land outside the church |
| EMBROIDER | Add extra to mixture of bromide and beer regularly (9) |
| ELECTS | Prefers carbon added to mixture of steel (6) |
| THORIUM | Hot stuff one added to mixture of hot rum (7) |
| REHYDRATE | Add water to mixture of red earth containing yttrium (9) |
| ELDESTHAND | Dealer's left distributing the LSD and ecstasy (6,4) |
| HEARTBREAK | Agony and ecstasy interrupting stag weekend? |
| MAKINGSURE | Checking American stars overwhelmed by knocking back liquor and ecstasy (6,4) |
| PNEUMATHODE | One may be breathing in hemp and shooting up methadone? |
| HADON | Did sport mete out methadone? (3,2) |
| DEDICATE | Reformed addict injecting methadone finally, finally sure to make pledge (8) |
| WORM | Having kicked heroin, methadone compound to encroach on spineless creature (8,4) |
| NEMATODE | Having kicked heroin, methadone compound to encroach on spineless creature (8,4) |
| CUSTOM | Copper starts to suspect traffic officer's methadone habit (6) |
| THEPIEDPIPEROFHAMELIN | Pilfer methadone with hippie, unfortunately one who led youths astray |
| MUCKY | Unclean methadone use can kill you for starters |
