| ELGRECO | Spanish painter, 1541-1614 (2,5) |
| PIZARRO | Francisco --, c1478-1541, Spanish conqueror of Peru (7) |
| RENI | Bolognese painter whose most celebrated work is his 1614 ceiling fresco Aurora, commissioned by Cardinal Scipione Borghese (4) |
| ROLFE | Groom of 1614 |
| CASAUBON | Isaac --, French classical scholar (1559-1614) (8) |
| NAPIER | Scottish mathematician who invented logarithms in 1614 (6) |
| DOWNSIDE | Roman Catholic school in Somerset founded in 1614 (8) |
| GREVILLE | Fulke ?, poet and dramatist; Chancellor of the Exchequer from 1614-21 (8) |
| ADDLED | The ___ Parliament of 1614 was dissolved by James VI and I after only eight weeks, no legislation having being passed (6) |
| POCAHONTAS | Native American woman who married English settler John Rolfe in 1614 (10) |
| DESOTO | Hernando, Spanish explorer who discovered the Mississippi River in 1541 (2,4) |
| SANTIAGO | Capital of Chile, founded by Spanish conquistador Pedro de Valdivia in 1541 (8) |
| HERNANDO | Spanish explorer and conquistador who in 1541 became the first European to cross the Mississippi River (8) |
| PARACELSUS | Philippus Aureolus ___, 1493-1541, German/Swiss alchemist and physician |
| ROCQUE | Jean-Francois de la ___, Sieur de Roberval (The first lieutenant General of New France, from 1541 to 1543) |
| PITTENWEEM | Fishing village in Fife (pop about 1,750), created a royal burgh in 1541 (10) |
| STRATHAVEN | Town in south Lanarkshire (pop about 7,500), created a burgh of barony in 1541 (10) |
| TURKEYCOCKS | Domestication of the common turkey was probably begun in pre-Columbian Mexico. The birds were first taken to Spain about 1519, and from Spain they spread throughout Europe, reaching England in 1541. W |
| AGUA | Guatemalan volcano named for a flood it caused in 1541 |
| SYLPH | Spirit of the air, as originating in the system of Swiss physician and alchemist Paracelsus (c. 1493-1541) (5) |