| REEDER | Small town in North Dakota that gave its name to a strain of wheat |
| FARGO | City in North Dakota that was made famous by the Coen brothers (5) |
| WELLS | Small town in north-east England (pop about 8,000) (5) |
| ALEXANDRA | Small town in north-east Victoria (pop about 6,000) (9) |
| WILKESBORO | -- and North --, two small towns in North Carolina (10) |
| ICES | Tends to a strain, say |
| TARSI | Bones grouped together thanks to a strain injury |
| STRESSED | Emphasised being subjected to a strain (8) |
| PEMBO | Abbreviated name of a county that gave its name to a breed of Corgi, where Tenby and Marloes form part of one of the three Welsh national parks (5) |
| SCHENGEN | Town in Luxembourg that gave its name to an agreement that provided for the removal of border controls between participating countries |
| LYME | Town in Connecticut that gave its name to a disease caused by a bite from an infected tick (4) |
| CAPRI | Island off the coast of Italy, in the Bay of Naples, that gave its name to a Ford model |
| RYEHOUSE | Building in Hertfordshire that gave its name to a 1683 plot to assassinate King Charles II and his brother James, Duke of York (3,5) |
| ALMA | Small river in Crimea that gave its name to the first battle of the Crimean War |
| WEIMAR | City in Thuringia, Germany, that gave its name to the republic that replaced the German Empire in 1919 |
| WINDRUSH | HMT Empire ___ , passenger liner that gave its name to a generation of Caribbean immigrants to the UK (8) |
| JODHPUR | Indian city in Rajasthan that gave its name to a style of riding breeches (7) |
| AXMINSTER | Devon town that gave its name to a type of carpet (9) |
| EBOLA | River in the Democratic Republic of the Congo that gave its name to a deadly virus (5) |
| ENGLAND | In part of the UK, New ___ is a strain of late-summer asters, while Calamagrostis x acutiflora '___' is a variegated ornamental grass! (7) |