| ROSEANNE | Sitcom that led to The Conner Family |
| BEWITCHED | 1960s American sitcom that led to the popularity of Samantha as a girl's name |
| BIGBANG | According to cosmological theories the event/explosion that led to the formation of the universe (3,4) |
| EDSA | The avenue in Manila (Philippines) which made concrete before the world the Filipinos' people power that led to the fall of Marcos from power |
| DUMBARTONOAKS | Historic estate in Washington, DC that was the scene of conferences in 1944 that led to the creation of the United Nations (9,4) |
| DUMBARTON | Estate in the District of Columbia, US, that hosted a 1944 conference that led to the formation of the United Nations (9) |
| OAKS | Estate in the District of Columbia, US, that hosted a 1944 conference that led to the formation of the United Nations (4) |
| NINETY | 19__, year of the terrible aeroplane crash that led to the village of Beckindale changing its name to Emmerdale (6-5) |
| REVOLUTION | Series of events in 1917 that led to the formation of the USSR, the Russian ... |
| IRANIAN | ____ Revolution, popular uprising that led to the overthrow of the Shah in the late 1970s (7) |
| EMS | German town associated with the 1870 dispatch from Bismarck that led to the outbreak of the Franco-Prussian War |
| MAASTRICHT | Dutch city associated with a treaty that led to the creation of the European Union and the Euro |
| ASWANDAM | The engineering feat that led to the creation of Lake Nasser? (5,3) |
| BROWNSEA | --- Island, Dorset location of a 1907 camp that led to the formation of the Scout movement (8) |
| ITINA | Memoir that led to the movie "What's Love Got to Do With It" |
| THEELEPHANTMAN | 1980 film that led to the creation of the Academy Award for Best Makeup |
| GIJANE | Movie in the joke that led to the Will Smith/Chris Rock slap |
| PIZARRO | Conquistador best known for his expeditions that led to the Spanish conquest of the Inca Empire (9,7) |
| FRANCISCO | Conquistador best known for his expeditions that led to the Spanish conquest of the Inca Empire (9,7) |
| OSS | Agency that led to the CIA |
