| DEWAR | Sir James --, inventor of the vacuum flask (5) |
| HARGREAVES | James --, inventor of the spinning jenny (10) |
| DYSON | James - - -, inventor and tycoon (5) |
| LASSO | Catch the girl taking the vacuum (5) |
| MILNE | Sir James, dedicatee of 'Castle' Class No. 7001 (5) |
| HARDY | Winemaker in three America's Cup challenges, Sir James ... (5) |
| FLUTE | Sir James Galway gained fame playing what? (5) |
| PAGET | Sir James ___, surgeon and pathologist (5) |
| THERMOS | Mother's to supply the vacuum flask (7) |
| SPEEDOFLIGHT | A fundamental constant of nature and physics defined by the vacuum propagation rate of electromagnetic radiation, exactly 299,792,458 metres per second (5,2,5) |
| SOUND | Acoustic wave propagated by means of vibrations transmitting through air or water, thus does not exist in the vacuum of space (5) |
| GERMAINEGREER | Who said "I didn't fight to get women out from behind the vacuum cleaner to get them on to the board of Hoover"? (8,5) |
| HOOVERDAMAGE | Result of forgetting to put the bag in the vacuum? |
| REYNOLDS | Co-founder and first president of the Royal Academy of Arts who was the second artist to have been honoured with a knighthood after Sir James Thornhill (8) |
| MURRAY | Sir James -; depicted in The Professor and the Madman, an early editor of what became the Oxford English Dictionary (6) |
| HELENSBURGH | Town on the north side of the Firth of Clyde in Scotland, named by Sir James Colquhoun after his wife (11) |
| RUG | I'm the one in the room that loves the vacuum. What am I? A ___ |
| PUMP | A device such as the vacuum chamber or "pneumatic engine" invented by Robert Boyle with the help of Robert Hooke (4) |
| AIR | There isn't any in the vacuum of space |
| GOLDENBOUGH | 'The ------ ', 1890 work by the Scottish anthropologist Sir James George Frazer subtitled A Study In Magic And Religion (6,5) |
