| TRILLIAN | Sing with Scotsman played by Sandra Dickinson in sci-fi comedy series The Hitchhiker's Guide to the Galaxy (8) |
| ADAMS | Author of the science fiction comedy series The Hitchhiker's Guide To The Galaxy, Douglas ... |
| DENT | Arthur, protagonist of Douglas Adams' comic science fiction series The Hitchhiker's Guide to the Galaxy (4) |
| GALAXY | 1981 BBC series: The Hitchhiker's Guide To The ___ (6) |
| GUIDE | Sci-fi comedy series created by Douglas Adams, The Hitchhiker's... to the Galaxy (5) |
| CAT | Character in sci-fi comedy Red Dwarf played by Danny John-jules since the first episode in 1988 (3) |
| ACE | Arnold Rimmer's alter ego in sci-fi comedy series Red Dwarf (3) |
| RED | 1988 British sci-fi comedy series about the adventures of the last human alive stranded on a mining spaceship: 2 wds. |
| NELLIEDINGLE | Emmerdale character played by Sandra Gough in 1995 and Maggie Tagney in 2000 |
| SPACE | Classic 1960s sci-fi comedy series, Lost in ----- (5) |
| EUREKA | Sci-fi comedy series with Colin Ferguson |
| MANIACMANSION | Joe Flaherty starred as Dr. Fred Edison on what early 1990s Sci-Fi comedy series?: 2 wds. |
| KILLINGEVE | BBC America drama whose title role is an MI5 agent played by Sandra Oh: 2 wds. |
| ACERIMMER | Alter ego of Chris Barrie's character in sci-fi comedy Red Dwarf (3,6) |
| JOHN | Beatle who will be played by Harris Dickinson in a Sam Mendes flick (4,6) |
| LENNON | Beatle who will be played by Harris Dickinson in a Sam Mendes flick (4,6) |
| DWARF | Sci-fi comedy series (Red -----) |
| AVENUEFIVE | Sci-Fi comedy series starring Hugh Laurie (6,4) |
| UPLOAD | Sci-fi comedy series about a virtual afterlife (6) |
| EVE | TV title role played by Sandra Oh |