| WIRING | Sending telegram about structure of brain and nervous system (6) |
| PRION | Protein particle thought to cause certain brain and nervous system diseases |
| LYME | ___ disease, a virus transmitted to humans by ticks, affecting the joints, heart and nervous system (4) |
| ANARCHIST | Troublemaker finds article first about structure |
| GLOBETROTTER | Keen tourist, German, given piece of brain and pig's foot (12) |
| MENINGITIS | Inflammation of brain & spinal cord membranes |
| SHIRTY | Peevish and nervous about a bit of dirt (6) |
| NEURAL | Lauren is upset and nervous (6) |
| ONEDGE | Third of troopers, say, retreat, upset and nervous |
| SHIFTY | Deceitful and nervous - put one foot in it |
| PENTUP | Like rage and nervous energy, often |
| SKULL | Framework enclosing the centre of sensation and intellectual and nervous activity (5) |
| BARBEDWIRE | Spiteful telegram about fencing supplies (6,4) |
| WORCESTERSHIRE | Telegram about her escorts wandering part of England (14) |
| TENSEDUP | Tup needs treatment when worried and nervous (6-2) |
| ARCTICSKUA | Seabird's bow and nervous response upset other birds (6,4) |
| WISEACRE | Telegram about marine initially confounded smart alec (8) |
| CABLECAR | Telegram about rare people carrier that's suspended (5,3) |
| BETEL | Transcribe telegram about a nut (5) |
| CAPABLE | Telegram about father being effective (7) |