| SPACELAB | Self-contained research laboratory developed by the European Space Agency (8) |
| TIMPEAKE | First British citizen selected as an astronaut by the European Space Agency (3,5) |
| GIOTTO | First deep-space mission by the European Space Agency, launched to study the 1986 appearance of Halley's Comet (6) |
| ROSETTA | Space probe launched in 2004 by the European Space Agency (7) |
| PEAKE | Tim ---, the first British citizen to be selected as an astronaut by the European Space Agency (5) |
| EUCLID | Space telescope launched by the European Space Agency in July 2023 to study dark matter and dark energy (6) |
| GALILEO | Global navigation satellite system created by the European Space Agency (7) |
| COLUMBUS | The European Space Agency's programme contributing to the International Space Station |
| ISRO | Indian space agency preparing for the upcoming Proba-3 mission with the European Space Agency. (abbvr) (4) |
| PARIS | City that is the headquarters of the European Space Agency (5) |
| CARAVELS | Light ships developed by the Portuguese in the 15th century (8) |
| MOON | With many missions planned there, the European Space Agency last week proposed a new time zone for this place (with "the") |
| FRENCHGUIANA | Where does the European Space Agency carry out its launches? (6,6) |
| ESA | In pinesap, you can find the European Space Agency! (1,1,1) |
| ARIANE | The European Space Agency uses rockets in this series |
| HERSCHEL | German-born British astronomer, d. 1822 - European Space Observatory (8) |
| TRIREMES | Galleys developed by the ancient Greeks as warships, with three banks of oars on each side (8) |
| ATOMBOMB | Weapon developed by the Manhattan Project (4-4) |
| RADIOONE | Trade uncovered over a hundred finalists in European space station (5,3) |
| COREL | Software company named for the Cowpland Research Laboratory, in turn for the founder Michael Cowpland |
