| MARACAIBO | Second-largest city of Venezuela, founded as Nueva Zamora in 1574 (9) |
| CARACAS | Capital and largest city of Venezuela, founded in 1567 (7) |
| CHARLESIX | Catherine de' Medici and Henry II's son who ruled as king of France from 1560 until his death in 1574 (7,1,1) |
| ANTONI | And 12 Across Prime Minister of Andorra succeeded by Xavier Espot Zamora in May 2019 (6,5) |
| MEDICI | Cosimo de' -; first grand duke of Tuscany from 1569 until his death in 1574 (6) |
| ROTTERDAM | The second-largest city of the Netherlands (9) |
| PORTONOVO | Capital and second-largest city of Benin by population, in the SE near the border with Nigeria (5-4) |
| SUCRE | Capital founded as Ciudad de la Plata de la Nueva Toledo |
| JODHPUR | Second-largest city of the Indian state of Rajasthan, founded by the military Chieftain Rao Jodha in 1459 (7) |
| SALTO | Second-largest city of Uruguay, on the east bank of the Uruguay River opposite the Argentine city of Concordia (5) |
| ARG | Home country of nueva cancion singer Mercedes Sosa: Abbr. |
| ESPOO | Second-largest city of Finland, in the south just west of Helsinki (5) |
| ALEPPO | Second-largest city of Syria, known in Arabic as Halab (6) |
| PLOVDIV | Second-largest city of Bulgaria; as Trimontium, the capital of Roman Thrace (7) |
| NOVISAD | Second-largest city of Serbia; capital of the autonomous province of Vojvodina (4,3) |
| GRAZ | Second-largest city of Austria by area; capital of the state of Styria (4) |
| LEON | Second-largest city of Nicaragua, replaced as the national capital by Managua in the 1850s (4) |
| TUCSON | Second-largest city of the US state of Arizona, known as 'the Old Pueblo' (6) |
| AHORA | Now, in Nueva York |
| ELDIARIO | Newspaper in La Paz and Nueva York |
