| FROGS | Second of the |
| AXIS | Second of the cervical vertebra, below the atlas at the top of the spine (4) |
| SCORPIO | Second of the three water signs of the zodiac, ruled by the planet Mars and the dwarf planet Pluto (7) |
| JOEL | The son of Pethuel in the Old Testament and the second of the twelve minor prophets |
| RETICULUM | Second of the four compartments of a ruminant mammal's stomach, located between the rumen and the omasum (9) |
| EDEN | The second of the 15 prime ministers who served during the 70-year reign of Queen Elizabeth II (4) |
| PLIOCENE | Second of the two epochs comprising the Neogene period, between the Miocene and the Pleistocene (8) |
| PRINCECASPIAN | Second of the seven novels of The Chronicles Of Narnia by English author C. S. Lewis, published in 1951 (6,7) |
| DIEHARDER | Tagline of the second of the John McClane series of film (3,6) |
| LATTER | The second of the two mentioned: the - |
| WOMAN | Wonder ___, title role played by Gal Gadot in the new movie out this week - the second of the Justice League films (pictured) (5) |
| SUMMER | The second of the violin concerti forming Vivaldi's The Four Seasons (6) |
| ANGER | Second of the five stages of grief, in the Kubler-Ross model |
| PURGATORIO | The second of the The Divine Comedy's three sections (10) |
| IDOLWORSHIP | Violation of the second of the Ten Commandments |
| SIMEON | Second of the six sons of Jacob and Leah in the Old Testament (Genesis 29) (6) |
| WHAT | The second of the five W's |
| CLATTER | Makes quite a noise at 100, being the second of the two to do it (7) |
| IDAHO | State from which I had returned on the second of the month (5) |
| TRAJAN | Second of the Five Good Emperors of Rome (98-117) |
